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Ubiquitylation in immune disorders and cancer: from molecular mechanisms to therapeutic implications

Conjugation of ubiquitin to proteins (ubiquitylation) has emerged to be one of the most crucial post-translational modifications controlling virtually all cellular processes. What was once regarded as a mere signal for protein degradation has turned out to be a major regulator of molecular signallin...

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Detalhes bibliográficos
Main Authors: Fulda, Simone, Rajalingam, Krishnaraj, Dikic, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407942/
https://ncbi.nlm.nih.gov/pubmed/22730341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201100707
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