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The hypoxic microenvironment upgrades stem-like properties of ovarian cancer cells

BACKGROUND: To study whether hypoxia influences the stem-like properties of ovarian cancer cells and their biological behavior under hypoxia. METHOD: Ovarian cancer cell lines ES-2 and OVCAR-3 were cultivated in different oxygen tensions for proliferation, cell cycling and invasion analyses. The clo...

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Autori principali: Liang, Dongming, Ma, Yuanyuan, Liu, Jian, Trope, Claes Goran, Holm, Ruth, Nesland, Jahn M, Suo, Zhenhe
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407800/
https://ncbi.nlm.nih.gov/pubmed/22642602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-201
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