Are platinum agents, paclitaxel and irinotecan effective for clear cell carcinoma of the ovary? DNA damage detected with γH2AX induced by anticancer agents

OBJECTIVES: Differences in the incidences and types of DNA damage induced by antitumor agents for clear cell carcinoma (CCC) were determined in 2 ovarian CCC cell lines using γH2AX. MATERIAL AND METHODS: The antitumor activity of anticancer agents, CDDP, CBDCA, PTX and SN-38, was examined using ovar...

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Detalhes bibliográficos
Main Authors: Takatori, Eriko, Shoji, Tadahiro, Kumagai, Seisuke, Sawai, Takashi, Kurose, Akira, Sugiyama, Toru
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407784/
https://ncbi.nlm.nih.gov/pubmed/22691365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1757-2215-5-16
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