Knockdown of PLC-gamma-2 and calmodulin 1 genes sensitizes human cervical adenocarcinoma cells to doxorubicin and paclitaxel

BACKGROUND: RNA interference (RNAi) is a powerful approach in functional genomics to selectively silence messenger mRNA (mRNA) expression and can be employed to rapidly develop potential novel drugs against a complex disease like cancer. However, naked siRNA being anionic is unable to cross the anio...

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Autores principales: Stanislaus, Anthony, Bakhtiar, Athirah, Salleh, Diyana, Tiash, Snigdha, Fatemian, Tahereh, Hossain, Sharif, Akaike, Toshihiro, Chowdhury, Ezharul Hoque
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2012
Materias:
Primary Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407783/
https://ncbi.nlm.nih.gov/pubmed/22709569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-12-30
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