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Activation of c-jun N-terminal kinase in spinal cord contributes to breast cancer induced bone pain in rats

BACKGROUND: The most frequent pain in patients with metastatic breast and prostate cancer is bone pain, which can be severe and difficult to treat. The mechanisms underlying this pain remain unclear. Here we investigated the role of c-jun N-terminal kinase (JNK) pathway in the spinal cord in cancer-...

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Detalhes bibliográficos
Main Authors: Wang, Xiao-Wei, Hu, Shan, Mao-Ying, Qi-Liang, Li, Qian, Yang, Chang-Jiang, Zhang, Hui, Mi, Wen-Li, Wu, Gen-Cheng, Wang, Yan-Qing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407760/
https://ncbi.nlm.nih.gov/pubmed/22681856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-5-21
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