Angiogenic Signalling Pathways Altered in Gliomas: Selection Mechanisms for More Aggressive Neoplastic Subpopulations with Invasive Phenotype

The angiogenesis process is a key event for glioma survival, malignancy and growth. The start of angiogenesis is mediated by a cascade of intratumoural events: alteration of the microvasculature network; a hypoxic microenvironment; adaptation of neoplastic cells and synthesis of pro-angiogenic facto...

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Detalhes bibliográficos
Main Authors: Bulnes, Susana, Bengoetxea, Harkaitz, Ortuzar, Naiara, Argandoña, Enrike G., Garcia-Blanco, Álvaro, Rico-Barrio, Irantzu, Lafuente, José V.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407647/
https://ncbi.nlm.nih.gov/pubmed/22852079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/597915
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