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A Bulky Biaryl Phosphine Ligand Allows for Palladium-Catalyzed Amidation of Five-Membered Heterocycles as Electrophiles

[Image: see text] Palladium-catalyzed amidation of five-membered heterocyclic bromides that contain multiple heteroatoms was achieved for the first time using the Pd/1 catalyst system. This system allows for efficient access to N-arylated imidazoles, pyrazoles, thiazoles, pyrroles, and thiophenes in...

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Autori principali: Su, Mingjuan, Buchwald, Stephen L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407381/
https://ncbi.nlm.nih.gov/pubmed/22473747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201201244
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