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Isolation of a human genomic fragment, co-amplified with c-Ki-ras, that affects plasmid supercoiling in E. coli.

Amplification of cellular proto-oncogenes has been implicated in the development of human malignancies. A library was constructed from genomic DNA extracted from a lung tumour, previously shown to carry an amplified c-Ki-ras 2 gene. Using a v-Ki-ras probe, a fragment with ras homology was isolated a...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Heighway, J, Geurts van Kessel, A H
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1987
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC340738/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3033603/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.8.3411
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