Comparison of the conformation of an oligonucleotide containing a central G-T base pair with the non-mismatch sequence by proton NMR.

We have recorded NOESY spectra of two non-selfcomplementary undecanucleotide duplexes. From the observed NOEs we do not detect any significant distortion of the helix when a G-C pair is replaced by a G-T pair and the normal interresidue connectivities can be followed through the mismatch site. We co...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Quignard, E, Fazakerley, G V, van der Marel, G, van Boom, J H, Guschlbauer, W
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1987
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC340737/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3033602/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.8.3397
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