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Grape seed proanthocyanidins reactivate silenced tumor suppressor genes in human skin cancer cells by targeting epigenetic regulators

Grape seed proanthocyanidins (GSPs) have been shown to have anti-skin carcinogenic effects in in vitro and in vivo models. However, the precise epigenetic molecular mechanisms remain unexplored. This study was designed to investigate whether GSPs reactivate silenced tumor suppressor genes following...

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Autores principales: Vaid, Mudit, Prasad, Ram, Singh, Tripti, Jones, Virginia, Katiyar, Santosh K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407315/
https://ncbi.nlm.nih.gov/pubmed/22749965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2012.06.013
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