Evaluation of Persistence of Resistant Variants with Ultra-Deep Pyrosequencing in Chronic Hepatitis C Patients Treated with Telaprevir

BACKGROUND & AIMS: Telaprevir, a hepatitis C virus NS3/4A protease inhibitor has significantly improved sustained viral response rates when given in combination with pegylated interferon alfa-2a and ribavirin, compared with current standard of care in hepatitis C virus genotype 1 infected patien...

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Detalhes bibliográficos
Main Authors: Thomas, Xiomara V., de Bruijne, Joep, Sullivan, James C., Kieffer, Tara L., Ho, Cynthia K. Y., Rebers, Sjoerd P., de Vries, Michel, Reesink, Hendrik W., Weegink, Christine J., Molenkamp, Richard, Schinkel, Janke
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407168/
https://ncbi.nlm.nih.gov/pubmed/22848441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041191
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