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Age-Associated Changes In Oxidative Stress and NAD(+) Metabolism In Human Tissue

Nicotinamide adenine dinucleotide (NAD(+)) is an essential electron transporter in mitochondrial respiration and oxidative phosphorylation. In genomic DNA, NAD(+) also represents the sole substrate for the nuclear repair enzyme, poly(ADP-ribose) polymerase (PARP) and the sirtuin family of NAD-depend...

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Autors principals: Massudi, Hassina, Grant, Ross, Braidy, Nady, Guest, Jade, Farnsworth, Bruce, Guillemin, Gilles J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407129/
https://ncbi.nlm.nih.gov/pubmed/22848760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042357
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