Placental Toll-Like Receptor 3 and Toll-Like Receptor 7/8 Activation Contributes to Preeclampsia in Humans and Mice

Preeclampsia (PE) is a pregnancy-specific hypertensive syndrome characterized by excessive maternal immune system activation, inflammation, and endothelial dysfunction. Toll-like receptor (TLR) 3 activation by double-stranded RNA (dsRNA) and TLR7/8 activation by single-stranded RNA (ssRNA) expressed...

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Autores principales: Chatterjee, Piyali, Weaver, Laura E., Doersch, Karen M., Kopriva, Shelley E., Chiasson, Valorie L., Allen, Samantha J., Narayanan, Ajay M., Young, Kristina J., Jones, Kathleen A., Kuehl, Thomas J., Mitchell, Brett M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407075/
https://ncbi.nlm.nih.gov/pubmed/22848646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041884
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