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Unusual structure, evolutionary conservation of non-coding sequences and numerous pseudogenes characterize the human H3.3 histone multigene family.

The genomic organization of the replication-independent, basally expressed, human H3.3 gene is atypical of traditional histone gene organization. The gene contains 3 introns totalling 7.8 kb and unusual direct repeats flank all three intron-exon splice junctions. The transcription initiation site wa...

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Bibliographic Details
Main Authors: Wells, D, Hoffman, D, Kedes, L
Format: Artigo
Language:Inglês
Published: 1987
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC340704/
https://ncbi.nlm.nih.gov/pubmed/3031613
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