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Effects of high-fat diet and physical activity on pyruvate dehydrogenase kinase-4 in mouse skeletal muscle

BACKGROUND: The expression of PDK4 is elevated by diabetes, fasting and other conditions associated with the switch from the utilization of glucose to fatty acids as an energy source. It is previously shown that peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α), a master regulator...

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Autori principali: Rinnankoski-Tuikka, Rita, Silvennoinen, Mika, Torvinen, Sira, Hulmi, Juha J, Lehti, Maarit, Kivelä, Riikka, Reunanen, Hilkka, Kainulainen, Heikki
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407034/
https://ncbi.nlm.nih.gov/pubmed/22682013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-7075-9-53
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