The balance between two isoforms of LEF-1 regulates colon carcinoma growth

BACKGROUND: Colon cancer is one of the most aggressive human malignancies, with a very poor prognosis. Although it has been suggested that different isoforms of the lymphoid enhancer factor (LEF-1) have opposing biological activities, the biological outcome of aberrant LEF-1 activation in colon canc...

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Main Authors: Wang, Shu-Hong, Nan, Ke-Jun, Wang, Yao-Chun, Wang, Wen-Juan, Tian, Tao
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407021/
https://ncbi.nlm.nih.gov/pubmed/22639890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-12-53
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