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The Helicase and RNaseIIIa Domains of Arabidopsis Dicer-Like1 Modulate Catalytic Parameters during MicroRNA Biogenesis(1)([C])([W])([OA])

Dicer-Like1 (DCL1), an RNaseIII endonuclease, and Hyponastic Leaves1 (HYL1), a double-stranded RNA-binding protein, are core components of the plant microRNA (miRNA) biogenesis machinery. hyl1 null mutants accumulate low levels of miRNAs and display pleiotropic developmental phenotypes. We report th...

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Detalhes bibliográficos
Main Authors: Liu, Chenggang, Axtell, Michael J., Fedoroff, Nina V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Plant Biologists 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406889/
https://ncbi.nlm.nih.gov/pubmed/22474216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1104/pp.112.193508
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