The Human Selenoprotein VCP-interacting Membrane Protein (VIMP) Is Non-globular and Harbors a Reductase Function in an Intrinsically Disordered Region

The human selenoprotein VIMP (VCP-interacting membrane protein)/SelS (selenoprotein S) localizes to the endoplasmic reticulum (ER) membrane and is involved in the process of ER-associated degradation (ERAD). To date, little is known about the presumed redox activity of VIMP, its structure and how th...

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Main Authors: Christensen, Lea Cecilie, Jensen, Njal Winther, Vala, Andrea, Kamarauskaite, Jurate, Johansson, Linda, Winther, Jakob Rahr, Hofmann, Kay, Teilum, Kaare, Ellgaard, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Protein Synthesis and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406722/
https://ncbi.nlm.nih.gov/pubmed/22700979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.346775
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