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The C-terminal fragment of axon guidance molecule Slit3 binds heparin and neutralizes heparin's anticoagulant activity

Slit3 is a large molecule with multiple domains and belongs to axon guidance families. To date, the biological functions of Slit3 are still largely unknown. Our recent study demonstrated that the N-terminal fragment of Slit3 is a novel angiogenic factor. In this study, we examined the biological fun...

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Detalhes bibliográficos
Main Authors: Condac, Eduard, Strachan, Heather, Gutierrez-Sanchez, Gerardo, Brainard, Benjamin, Giese, Christina, Heiss, Christian, Johnson, Darryl, Azadi, Parastoo, Bergmann, Carl, Orlando, Ron, Esmon, Charles T, Harenberg, Job, Moremen, Kelley, Wang, Lianchun
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406619/
https://ncbi.nlm.nih.gov/pubmed/22641771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cws087
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