14-3-3 Protects against stress-induced apoptosis

Expression of human Bax, a cardinal regulator of mitochondrial membrane permeabilization, causes death in yeast. We screened a human cDNA library for suppressors of Bax-mediated yeast death and identified human 14-3-3β/α, a protein whose paralogs have numerous chaperone-like functions. Here, we show...

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Autori principali: Clapp, C, Portt, L, Khoury, C, Sheibani, S, Norman, G, Ebner, P, Eid, R, Vali, H, Mandato, C A, Madeo, F, Greenwood, M T
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406589/
https://ncbi.nlm.nih.gov/pubmed/22785534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.90
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