Neonatal Phytoestrogen Exposure Alters Oviduct Mucosal Immune Response to Pregnancy and Affects Preimplantation Embryo Development in the Mouse

Treatment of neonatal mice with the phytoestrogen genistein (50 mg/kg/day) results in complete female infertility caused in part by preimplantation embryo loss in the oviduct between Days 2 and 3 of pregnancy. We previously demonstrated that oviducts of genistein-treated mice are “posteriorized” as...

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Bibliographic Details
Main Authors: Jefferson, Wendy N., Padilla-Banks, Elizabeth, Phelps, Jazma Y., Cantor, Amy M., Williams, Carmen J.
Format: Artigo
Language:Inglês
Published: Society for the Study of Reproduction, Inc. 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406554/
https://ncbi.nlm.nih.gov/pubmed/22553218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.112.099846
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