Innate immune activation in neonatal tracheal aspirates suggests endotoxin-driven inflammation

BACKGROUND: Tracheal aspirates (TAs) from critically ill neonates accumulate bacterial endotoxin and demonstrate mobilization of endotoxin-binding proteins, but the potential bioactivity of endotoxin in TAs is unknown. We characterized innate immune activation in TAs of mechanically ventilated neona...

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Bibliographic Details
Main Authors: Nathe, Katheryn E., Mancuso, Christy J., Parad, Richard, Van Marter, Linda J., Martin, Camilia R., Stoler-Barak, Liat, Philbin, Victoria J., Phillips, Michele F., Palmer, Christine D., Levy, Ofer
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
Subjects:
Clinical Investigation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406551/
https://ncbi.nlm.nih.gov/pubmed/22580716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2012.61
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