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The chemokine CXCL12 and the HIV-1 envelope protein gp120 regulate spontaneous activity of Cajal–Retzius cells in opposite directions

Activation of the CXC chemokine receptor 4 (CXCR4) in Cajal–Retzius cells by CXC chemokine ligand 12 (CXCL12) is important for controlling their excitability. CXCR4 is also a co-receptor for the glycoprotein 120 (gp120) of the envelope of the human immunodeficiency virus type 1 (HIV-1), and binding...

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Autori principali: Marchionni, Ivan, Beaumont, Michael, Maccaferri, Gianmaria
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406399/
https://ncbi.nlm.nih.gov/pubmed/22473778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.224873
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