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A new signalling pathway for parallel fibre presynaptic type 4 metabotropic glutamate receptors (mGluR4) in the rat cerebellar cortex

In the rodent cerebellum, pharmacological activation of mGluR4 acutely depresses excitatory synaptic transmission at parallel fibre–Purkinje cell synapses. This depression involves the inhibition of presynaptic calcium (Ca(2+)) influx that ultimately controls glutamate release. In this study, we inv...

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Detalles Bibliográficos
Main Authors: Abitbol, Karine, McLean, Heather, Bessiron, Thomas, Daniel, Hervé
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406385/
https://ncbi.nlm.nih.gov/pubmed/22570379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.232074
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