Beta Amyloid Differently Modulate Nicotinic and Muscarinic Receptor Subtypes which Stimulate in vitro and in vivo the Release of Glycine in the Rat Hippocampus

Using both in vitro (hippocampal synaptosomes in superfusion) and in vivo (microdialysis) approaches we investigated whether and to what extent β amyloid peptide 1–40 (Aβ 1–40) interferes with the cholinergic modulation of the release of glycine (GLY) in the rat hippocampus. The nicotine-evoked over...

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Detalhes bibliográficos
Main Authors: Zappettini, Stefania, Grilli, Massimo, Olivero, Guendalina, Mura, Elisa, Preda, Stefania, Govoni, Stefano, Salamone, Alessia, Marchi, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2012
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406330/
https://ncbi.nlm.nih.gov/pubmed/22866037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2012.00146
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