Mouse and human eosinophils degranulate in response to PAF and lysoPAF via a PAF-receptor independent mechanism: evidence for a novel receptor()

Platelet activating factor (PAF; 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) is a phospholipid mediator released from activated macrophages, mast cells, and basophils that promotes pathophysiologic inflammation. Eosinophil responses to PAF are complex and incompletely elucidated. We show here th...

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Detalhes bibliográficos
Main Authors: Dyer, Kimberly D., Percopo, Caroline M., Xie, Zhihui, Yang, Zhao, Kim, John Dongil, Davoine, Francis, Lacy, Paige, Moqbel, Redwan, Druey, Kirk M., Rosenberg, Helene F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406327/
https://ncbi.nlm.nih.gov/pubmed/20421642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0904043
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