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Structural determinants of the supramolecular organization of G protein-coupled receptors in bilayers

The G protein-coupled receptor (GPCR) rhodopsin self-assembles into supramolecular structures in native bilayers, but the structural determinants of receptor oligomerization are not known. We carried out multiple self-assembly coarse-grained molecular dynamics (CGMD) simulations of model membranes c...

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Hlavní autoři: Periole, Xavier, Knepp, Adam M., Sakmar, Thomas P., Marrink, Siewert J., Huber, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406292/
https://ncbi.nlm.nih.gov/pubmed/22679925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja303286e
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