Parthenolide-induced apoptosis of hepatic stellate cells and anti-fibrotic effects in an in vivo rat model

Parthenolide (PT), a sesquiterpene lactone derived from the plant feverfew, has pro-apoptotic activity in a number of cancer cell types. We assessed whether PT induces the apoptosis of hepatic stellate cells (HCSs) and examined its effects on hepatic fibrosis in an in vivo model. The effects of PT o...

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Detalhes bibliográficos
Main Authors: Kim, In Hee, Kim, Sang Wook, Kim, Seong Hun, Lee, Seung Ok, Lee, Soo Teik, Kim, Dae-Ghon, Lee, Mi-Jin, Park, Woo Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Biochemistry and Molecular Biology 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406290/
https://ncbi.nlm.nih.gov/pubmed/22581380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2012.44.7.051
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