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Palmitoylation by DHHC3 is critical for the function, expression, and stability of integrin α6β4

The laminin-binding integrin α6β4 plays key roles in both normal epithelial and endothelial cells and during tumor cell progression, metastasis, and angiogenesis. Previous cysteine mutagenesis studies have suggested that palmitoylation of α6β4 protein supports a few integrin-dependent functions and...

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Detalhes bibliográficos
Main Authors: Sharma, Chandan, Rabinovitz, Isaac, Hemler, Martin E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406256/
https://ncbi.nlm.nih.gov/pubmed/22314500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-012-0924-6
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