Activation and Proteolytic Activity of the Treponema pallidum Metalloprotease, Pallilysin

Treponema pallidum is a highly invasive pathogen that undergoes rapid dissemination to establish widespread infection. Previous investigations identified the T. pallidum adhesin, pallilysin, as an HEXXH-containing metalloprotease that undergoes autocatalytic cleavage and degrades laminin and fibrino...

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Bibliographische Detailangaben
Hauptverfasser: Houston, Simon, Hof, Rebecca, Honeyman, Lisa, Hassler, Julia, Cameron, Caroline E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406077/
https://ncbi.nlm.nih.gov/pubmed/22910436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002822
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