ExoU Activates NF-κB and Increases IL-8/KC Secretion during Pseudomonas aeruginosa Infection

ExoU, a Pseudomonas aeruginosa cytotoxin injected into host cytosol by type III secretion system, exhibits a potent proinflammatory activity that leads to a marked recruitment of neutrophils to infected tissues. To evaluate the mechanisms that account for neutrophil infiltration, we investigated the...

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Detalhes bibliográficos
Main Authors: de Lima, Carolina Diettrich Mallet, Calegari-Silva, Teresa Cristina, Pereira, Renata Meirelles Santos, Santos, Sabrina Alves de Oliveira Lima, Lopes, Ulisses Gazos, Plotkowski, Maria-Cristina Maciel, Saliba, Alessandra Mattos
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406076/
https://ncbi.nlm.nih.gov/pubmed/22848596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041772
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