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Elucidation of Xenobiotic Metabolism Pathways in Human Skin and Human Skin Models by Proteomic Profiling

BACKGROUND: Human skin has the capacity to metabolise foreign chemicals (xenobiotics), but knowledge of the various enzymes involved is incomplete. A broad-based unbiased proteomics approach was used to describe the profile of xenobiotic metabolising enzymes present in human skin and hence indicate...

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Main Authors: van Eijl, Sven, Zhu, Zheying, Cupitt, John, Gierula, Magdalena, Götz, Christine, Fritsche, Ellen, Edwards, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406074/
https://ncbi.nlm.nih.gov/pubmed/22848577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041721
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