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Empirical Validation of Pooled Whole Genome Population Re-Sequencing in Drosophila melanogaster
The sequencing of pooled non-barcoded individuals is an inexpensive and efficient means of assessing genome-wide population allele frequencies, yet its accuracy has not been thoroughly tested. We assessed the accuracy of this approach on whole, complex eukaryotic genomes by resequencing pools of lar...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3406057/ https://ncbi.nlm.nih.gov/pubmed/22848651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041901 |
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