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Cardiospheres recapitulate a niche-like microenvironment rich in stemness and cell-matrix interactions, rationalizing their enhanced functional potency for myocardial repair

Cardiac stem cells are promising candidates for use in myocardial regenerative therapy. We test the hypothesis that growing cardiac-derived cells as three-dimensional cardiospheres may recapitulate a stem cell niche-like microenvironment, favoring cell survival and enhancing functional benefit after...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Tao-Sheng, Cheng, Ke, Lee, Shuo-Tsan, Matsushita, Satoshi, Davis, Darryl, Malliaras, Konstantinos, Zhang, Yiqiang, Matsushita, Noriko, Smith, Rachel Ruckdeschel, Marbán, Eduardo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405979/
https://ncbi.nlm.nih.gov/pubmed/20882531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.532
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