Identifying individual DNA species in a complex mixture by precisely measuring the spacing between nicking restriction enzymes with atomic force microscope

We discuss a novel atomic force microscope-based method for identifying individual short DNA molecules (<5000 bp) within a complex mixture by measuring the intra-molecular spacing of a few sequence-specific topographical labels in each molecule. Using this method, we accurately determined the rel...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Reed, Jason, Hsueh, Carlin, Lam, Miu-Ling, Kjolby, Rachel, Sundstrom, Andrew, Mishra, Bud, Gimzewski, J. K.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Royal Society 2012
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405743/
https://ncbi.nlm.nih.gov/pubmed/22456455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2012.0024
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares