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Serum from patients with SLE instructs monocytes to promote IgG and IgA plasmablast differentiation
The development of autoantibodies is a hallmark of systemic lupus erythematosus (SLE). SLE serum can induce monocyte differentiation into dendritic cells (DCs) in a type I IFN–dependent manner. Such SLE-DCs activate T cells, but whether they promote B cell responses is not known. In this study, we d...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3405503/ https://ncbi.nlm.nih.gov/pubmed/22689824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111644 |
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