miR-146a regulates mechanotransduction and pressure-induced inflammation in small airway epithelium

Mechanical ventilation generates biophysical forces, including high transmural pressures, which exacerbate lung inflammation. This study sought to determine whether microRNAs (miRNAs) respond to this mechanical force and play a role in regulating mechanically induced inflammation. Primary human smal...

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Bibliografiska uppgifter
Huvudupphovsmän: Huang, Yan, Crawford, Melissa, Higuita-Castro, Natalia, Nana-Sinkam, Patrick, Ghadiali, Samir N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Federation of American Societies for Experimental Biology 2012
Ämnen:
Research Communications
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405275/
https://ncbi.nlm.nih.gov/pubmed/22593544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-199240
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