Maternal low-protein diet up-regulates the neuropeptide Y system in visceral fat and leads to abdominal obesity and glucose intolerance in a sex- and time-specific manner

Neuropeptide Y (NPY) mediates stress-induced obesity in adult male mice by activating its Y2 receptor (Y2R) in visceral adipose tissue (VAT). Here, we studied whether the NPY-Y2R system is also activated by maternal low-protein diet (LPD) and linked to obesity in offspring. Prenatal LPD offspring ha...

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Bibliographic Details
Main Authors: Han, Ruijun, Li, Aiyun, Li, Lijun, Kitlinska, Joanna B., Zukowska, Zofia
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2012
Subjects:
Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405267/
https://ncbi.nlm.nih.gov/pubmed/22539639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-203943
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