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Utilization of DNA photolyase, pyrimidine dimer endonucleases, and alkali hydrolysis in the analysis of aberrant ABC excinuclease incisions adjacent to UV-induced DNA photoproducts.

ABC excinuclease of Escherichia coli removes 6-4 photoproducts and pyrimidine dimers from DNA by making two single strand incisions, one 8 phosphodiester bonds 5' and another 4 or 5 phosphodiester bonds 3' to the lesion. We describe in this communication a method, which utilizes DNA photol...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Myles, G M, Van Houten, B, Sancar, A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 1987
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC340520/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3547334/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.3.1227
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