Specification Of Midbrain Dopamine Neurons From Primate Pluripotent Stem Cells

By sequentially applying sonic hedgehog (C25II) and CHIR99021 (GSK3β inhibitor) to induce the midbrain floor plate progenitors and fibroblast growth factor 8 (FGF8) to promote dopaminergic differentiation in a chemically defined medium, we have established a robust system for generation of midbrain...

Full description

Saved in:
Bibliographic Details
Main Authors: Xi, Jiajie, Liu, Yan, Liu, Huisheng, Chen, Hong, Emborg, Marina E., Zhang, Su-Chun
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405174/
https://ncbi.nlm.nih.gov/pubmed/22696177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1152
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items