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Specification Of Midbrain Dopamine Neurons From Primate Pluripotent Stem Cells

By sequentially applying sonic hedgehog (C25II) and CHIR99021 (GSK3β inhibitor) to induce the midbrain floor plate progenitors and fibroblast growth factor 8 (FGF8) to promote dopaminergic differentiation in a chemically defined medium, we have established a robust system for generation of midbrain...

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Bibliografske podrobnosti
Main Authors: Xi, Jiajie, Liu, Yan, Liu, Huisheng, Chen, Hong, Emborg, Marina E., Zhang, Su-Chun
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405174/
https://ncbi.nlm.nih.gov/pubmed/22696177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1152
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