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Specification Of Midbrain Dopamine Neurons From Primate Pluripotent Stem Cells
By sequentially applying sonic hedgehog (C25II) and CHIR99021 (GSK3β inhibitor) to induce the midbrain floor plate progenitors and fibroblast growth factor 8 (FGF8) to promote dopaminergic differentiation in a chemically defined medium, we have established a robust system for generation of midbrain...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3405174/ https://ncbi.nlm.nih.gov/pubmed/22696177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1152 |
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