Zoledronate Inhibits Ischemia-Induced Neovascularization by Impairing the Mobilization and Function of Endothelial Progenitor Cells

BACKGROUND: Bisphosphonates are a class of pharmacologic compounds that are commonly used to treat postmenopausal osteoporosis and malignant osteolytic processes. Studies have shown that bone marrow-derived endothelial progenitor cells (EPCs) play a significant role in postnatal neovascularization....

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Main Authors: Tsai, Shih-Hung, Huang, Po-Hsun, Chang, Wei-Chou, Tsai, Hsiao-Ya, Lin, Chih-Pei, Leu, Hsin-Bang, Wu, Tao-Cheng, Chen, Jaw-Wen, Lin, Shing-Jong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405104/
https://ncbi.nlm.nih.gov/pubmed/22848429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041065
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