TNF-Overexpression in Borna Disease Virus-Infected Mouse Brains Triggers Inflammatory Reaction and Epileptic Seizures

Proinflammatory state of the brain increases the risk for seizure development. Neonatal Borna disease virus (BDV)-infection of mice with neuronal overexpression of tumor necrosis factor-α (TNF) was used to investigate the complex relationship between enhanced cytokine levels, neurotropic virus infec...

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Bibliographic Details
Main Authors: Kramer, Katharina, Schaudien, Dirk, Eisel, Ulrich L. M., Herzog, Sibylle, Richt, Jürgen A., Baumgärtner, Wolfgang, Herden, Christiane
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405098/
https://ncbi.nlm.nih.gov/pubmed/22848506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041476
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