Genetic Markers Enhance Coronary Risk Prediction in Men: The MORGAM Prospective Cohorts

BACKGROUND: More accurate coronary heart disease (CHD) prediction, specifically in middle-aged men, is needed to reduce the burden of disease more effectively. We hypothesised that a multilocus genetic risk score could refine CHD prediction beyond classic risk scores and obtain more precise risk est...

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Main Authors: Hughes, Maria F., Saarela, Olli, Stritzke, Jan, Kee, Frank, Silander, Kaisa, Klopp, Norman, Kontto, Jukka, Karvanen, Juha, Willenborg, Christina, Salomaa, Veikko, Virtamo, Jarmo, Amouyel, Phillippe, Arveiler, Dominique, Ferrières, Jean, Wiklund, Per-Gunner, Baumert, Jens, Thorand, Barbara, Diemert, Patrick, Trégouët, David-Alexandre, Hengstenberg, Christian, Peters, Annette, Evans, Alun, Koenig, Wolfgang, Erdmann, Jeanette, Samani, Nilesh J., Kuulasmaa, Kari, Schunkert, Heribert
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405046/
https://ncbi.nlm.nih.gov/pubmed/22848412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040922
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