The Odyssey of Hsp60 from Tumor Cells to Other Destinations Includes Plasma Membrane-Associated Stages and Golgi and Exosomal Protein-Trafficking Modalities

BACKGROUND: In a previous work we showed for the first time that human tumor cells secrete Hsp60 via exosomes, which are considered immunologically active microvesicles involved in tumor progression. This finding raised questions concerning the route followed by Hsp60 to reach the exosomes, its loca...

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Bibliografiske detaljer
Main Authors: Campanella, Claudia, Bucchieri, Fabio, Merendino, Anna M., Fucarino, Alberto, Burgio, Giosalba, Corona, Davide F. V., Barbieri, Giovanna, David, Sabrina, Farina, Felicia, Zummo, Giovanni, de Macario, Everly Conway, Macario, Alberto J. L., Cappello, Francesco
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405006/
https://ncbi.nlm.nih.gov/pubmed/22848686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042008
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