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Array CGH improves detection of mutations in the GALC gene associated with Krabbe disease

BACKGROUND: Krabbe disease is an autosomal recessive lysosomal storage disorder caused by mutations in the GALC gene. The most common mutation in the Caucasian population is a 30-kb deletion of exons 11 through 17. There are few other reports of intragenic GALC deletions or duplications, due in part...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tanner, Alice K, Chin, Ephrem L H, Duffner, Patricia K, Hegde, Madhuri
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404939/
https://ncbi.nlm.nih.gov/pubmed/22704718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1172-7-38
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