Renoprotective effects of anti-TGF-β antibody and antihypertensive therapies in Dahl S rats

This study examined the effects of anti-TGF-β antibody (1D11) therapy in Dahl S (S) rats fed a 4% NaCl diet. Baseline renal expression of TGF-β1 and the degree of injury were lower in female than male S rats maintained on a 0.4% NaCl diet. 4% NaCl diet increased mean arterial pressure (MAP), protein...

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Detalhes bibliográficos
Main Authors: Murphy, Sydney R., Dahly-Vernon, Annette J., Dunn, Kathryn M. J., Chen, Chun Cheng Andy, Ledbetter, Steven R., Williams, Jan M., Roman, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Fluid and Electrolyte Homeostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404639/
https://ncbi.nlm.nih.gov/pubmed/22538513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00263.2011
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