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CaMKII inhibition hyperpolarizes membrane and blocks nitrergic IJP by closing a Cl(−) conductance in intestinal smooth muscle

The ionic basis of nitrergic “slow'” inhibitory junction potential (sIJP) is not fully understood. The purpose of the present study was to determine the nature and the role of calmodulin-dependent protein kinase II (CaMKII)-dependent ion conductance in nitrergic neurotransmission at the intesti...

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Detalhes bibliográficos
Main Authors: He, Xue-Dao, Goyal, Raj K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404568/
https://ncbi.nlm.nih.gov/pubmed/22538403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00102.2012
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