Toll-like receptor 4 regulates early endothelial activation during ischemic acute kidney injury

Ischemic acute kidney injury (AKI) triggers an inflammatory response which exacerbates injury that requires increased expression of endothelial adhesion molecules. To study this further, we used in situ hybridization, immunohistology, and isolated endothelial cells, and found increased Toll-like rec...

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Bibliographic Details
Main Authors: Chen, Jianlin, John, Reji, Richardson, James A., Shelton, John M., Zhou, Xin J., Wang, Yanxia, Wu, Qing Qing, Hartono, John R., Winterberg, Pamela D., Lu, Christopher Y.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404515/
https://ncbi.nlm.nih.gov/pubmed/20927041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2010.381
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