Immunosuppression Decreases Inflammation and Increases AAV6-hSERCA2a-Mediated SERCA2a Expression

The calcium pump SERCA2a (sarcoplasmic reticulum calcium ATPase 2a), which plays a central role in cardiac contraction, shows decreased expression in heart failure (HF). Increasing SERCA2a expression in HF models improves cardiac function. We used direct cardiac delivery of adeno-associated virus en...

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Detalhes bibliográficos
Main Authors: Zhu, Xiaodong, McTiernan, Charles F., Rajagopalan, Navin, Shah, Hemal, Fischer, David, Toyoda, Yoshiya, Letts, Dustin, Bortinger, Jonathan, Gibson, Gregory, Xiang, Wenyu, McCurry, Kenneth, Mathier, Michael, Glorioso, Joseph C., London, Barry
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404422/
https://ncbi.nlm.nih.gov/pubmed/22482463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2011.108
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