Insulin-Induced Endothelial Cell Cortical Actin Filament Remodeling: A Requirement for Trans-Endothelial Insulin Transport

Insulin's trans-endothelial transport (TET) is critical for its metabolic action on muscle and involves trafficking of insulin bound to its receptor (or at high insulin concentrations, the IGF-I receptor) via caveolae. However, whether caveolae-mediated insulin TET involves actin cytoskeleton o...

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Bibliographic Details
Main Authors: Wang, Hong, Wang, Aileen X., Barrett, Eugene J.
Format: Artigo
Language:Inglês
Published: Endocrine Society 2012
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404295/
https://ncbi.nlm.nih.gov/pubmed/22734037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1003
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